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•How Missing Checklists and Protocols are Costing Lives in Nepal’s ERs•Why Your Lungs May Hold the Secret to Your Stress Levels•Walking in Fear: Why Nepal’s Streets Aren't Safe and the Race to Stop a "Hidden Killer"•Why Poor Living and Working Conditions are Shattering the Mental Health of Nepali Workers•Silent Suffering: Why Nepal’s Doctors and Nurses Are Not Reporting Child Abuse•New Study Highlights Metabolism Risks in Combination Antidepressant Therapy in Nepal•New Study Reveals Hidden Environmental Drivers Behind Nepal’s Ongoing Cholera Battle•The Silent Pandemic: Kathmandu’s Poultry Industry Is Breeding Untreatable Superbugs•The Silent Emergency: Domestic Violence and the Mental Health Crisis Among Nepalese Women•Nepal’s Drug-Resistant TB Rates Hold Steady, but New Antibiotic Resistance Sparks Concern•How Missing Checklists and Protocols are Costing Lives in Nepal’s ERs•Why Your Lungs May Hold the Secret to Your Stress Levels•Walking in Fear: Why Nepal’s Streets Aren't Safe and the Race to Stop a "Hidden Killer"•Why Poor Living and Working Conditions are Shattering the Mental Health of Nepali Workers•Silent Suffering: Why Nepal’s Doctors and Nurses Are Not Reporting Child Abuse•New Study Highlights Metabolism Risks in Combination Antidepressant Therapy in Nepal•New Study Reveals Hidden Environmental Drivers Behind Nepal’s Ongoing Cholera Battle•The Silent Pandemic: Kathmandu’s Poultry Industry Is Breeding Untreatable Superbugs•The Silent Emergency: Domestic Violence and the Mental Health Crisis Among Nepalese Women•Nepal’s Drug-Resistant TB Rates Hold Steady, but New Antibiotic Resistance Sparks Concern

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Live updates directly from PubMed Research

What are the vectors in European livestock farms? Case studies in Hungary and Spain

CONCLUSIONS: The originality of this study lies in its multi-vector description of three arthropod communities associated with three livestock species (cattle, sheep, pigs) on farms located in two European countries with contrasting environments and climates. The study demonstrated the coexistence of 16 arthropod species of veterinary and public health relevance in the surveyed farms. Their diversity and abundance were influenced by geographical contrasts between Mediterranean and Central...

May 8, 2026Read Abstract →

Tools to help patients and other stakeholders' input into choice of intercurrent event strategy for estimands in randomised trials

CONCLUSIONS: We developed three tools to help researchers to have conversations with patients and other stakeholders about estimands, and how intercurrent events should be incorporated into the target estimand for a randomised trial. Further work to evaluate the tools in real-world settings across different stakeholder groups could help to validate the tools and reveal any further refinements necessary to improve their utility.

May 8, 2026Read Abstract →

Chinese guidelines for HER2-targeted therapy in gastric and gastroesophageal junction adenocarcinoma (2025 Edition)

Gastric and gastroesophageal junction adenocarcinoma (GC/GEJC) poses a substantial clinical burden in China. This updated guideline introduces a refined human epidermal growth factor receptor 2 (HER2) classification system (high, intermediate, low, absent) to redefine patient stratification for targeted therapy. It integrates cutting-edge evidence on standardized detection-including immunohistochemistry, in situ hybridization, and liquid biopsy-to overcome spatial-temporal heterogeneity. Recent...

May 8, 2026Read Abstract →

An updated pharmacovigilance evidence from U.S. tobacco problem reports following the FDA safety communication on e-cigarettes and seizures

CONCLUSIONS: Seizures represent a pharmacovigilance signal associated with e-cigarette use. Respiratory events were reported more often among e-cigarette users but did not meet conservative Bayesian thresholds. These findings highlight the need for continued surveillance, studies, and regulatory vigilance regarding the safety of e-cigarettes.

May 8, 2026Read Abstract →

Chinese expert consensus on the standardized application of generative artificial intelligence large models in ophthalmology (2026)

With the rapid development of generative artificial intelligence (AI) technologies and large AI models, these technologies are expected to play an important role in multiple aspects of medical workflows in ophthalmology. However, their rapid and widespread adoption has also introduced multiple challenges regarding application specifications, ethical constraints, and legal compliance. To ensure the safe, effective, and compliant application of generative AI large models in ophthalmology, the...

May 8, 2026Read Abstract →

Updates in Person-Centered Rehabilitation for Critically Ill Patients

Modern patient-centered rehabilitation for critically ill patients focuses on physical, cognitive, psychological, and social recovery to reduce long-term impairments after critical illness. Core strategies include the ABCDEF (A2F) bundle/ICU Liberation, humanization programs, and symptom management. Based on the capabilities of individual patients, frequent assessments in these dimensions are performed to develop person-centered goals and interventions. Early mobilization, cognitive stimulation,...

May 8, 2026Read Abstract →

Parents' experiences during their child's stay in the NICU or PICU: A scoping review

CONCLUSIONS: Attitudes, communication, and parental involvement of healthcare professionals in their child's care and decision-making significantly impact parents' experiences and stress levels. This can have short- and long-term effects on parents and their child. Understanding parents' experiences in the NICU and PICU will enable nurses to recognize their experiences and needs and help them to improve the care they provide.

May 8, 2026Read Abstract →

Management updates in heart failure with mildly reduced or preserved ejection fraction

Heart failure (HF) is a clinical syndrome characterized by structural or functional impairments in ventricular filling or the ejection of blood from the heart. In the United States, HF represents a growing public health concern, affecting an estimated 6.7 million adults 20 years or older, with prevalence expected to continue rising. Despite advances in guideline-directed medical therapy (GDMT), rates of hospitalization and mortality remain high. Therapeutic options are particularly limited for...

May 8, 2026Read Abstract →

Variation in management of febrile infants younger than 90 days across London: a retrospective cohort study

Evaluate variation in care of febrile infants presenting to London hospitals and adherence to national Clinical Practice Guidelines (CPGs). Retrospective multicentre cohort study conducted at 21 London hospitals. Infants ≤ 90 days of age presenting with fever or caregiver reported fever between 1st April 2021-31st March 2022 were included. Outcome measures were variations in patient management and adherence to national CPGs. Of 2,008 presentations, 41.1% were febrile during assessment. 73.7% had...

May 8, 2026Read Abstract →

Mortality and cancer incidence in a large cohort of lead-exposed workers

CONCLUSION: High blood lead levels were associated with several causes of mortality and cancer incidence, most markedly lung cancer. While lung cancer trends might be related to smoking, there is no a priori reason why workers with higher blood lead would have smoked more and, in a subset of 200 workers with smoking data, there was no such evidence. The lung cancer rate ratios in the order of 2.0-2.5 are also very unlikely to be explained by smoking differences.

May 8, 2026Read Abstract →

Interventions to enhance work participation in people with chronic pain: A systematic review and meta-analysis including analysis of complex psychological intervention components

CONCLUSION: Complex psychological interventions can positively influence work outcomes for people with chronic pain. Future research should prioritize high-quality studies and incorporate the five components to enhance work-focussed support.

May 8, 2026Read Abstract →

Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health

BACKGROUND: Iron overload (IO) disorders, including thalassaemias, hereditary haemochromatosis, and transfusion-dependent anaemias, represent a growing clinical challenge with widespread systemic implications. Reproductive dysfunction remains severely underappreciated despite its high prevalence. Hormonal changes due to iron toxicity are frequently reported, yet are seldom the focus of reproductive medicine, causing fragmented knowledge, inconsistent clinical approaches, and a lack of consensus...

May 8, 2026Read Abstract →

Disclosing mental health in medical education: A global qualitative meta-synthesis

CONCLUSION: Disclosure of mental health disorders in medical education is a negotiated, relational process embedded within socio-cultural and institutional power dynamics. This synthesis advances understanding by situating disclosure within disability and critical theory frameworks, highlighting how ableism and professional identity norms perpetuate silence. Addressing these structural forces through inclusive policies and psychologically safe learning cultures is essential to normalising...

May 8, 2026Read Abstract →

Pediatric lung transplantation in 2026: recent changes and current challenges

PURPOSE OF REVIEW: Lung transplantation has evolved as an accepted therapy in carefully selected children with end-stage lung disease, offering prolonged survival and improved health-related quality of life (HRQoL). Pediatric lung transplantation is complex and multilayered and differs from adult transplant. Specific aspects of pediatric lung transplantation will be reviewed, updates on recent developments in the field will be shared, and current challenges will be discussed.

May 8, 2026Read Abstract →

The International Glossary on Infertility and Fertility Care, 2025†

STUDY QUESTION: What updates of the International Glossary on Infertility and Fertility Care are required, to reflect contemporary scientific knowledge, social needs, and inclusive definitions, while harmonizing international communication across clinical, research, policy, and public domains?

May 8, 2026Read Abstract →
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