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Physiotherapist's Management of Suspected Cauda Equina Syndrome in the United Kingdom: A National Survey

BACKGROUND AND PURPOSE: Cauda Equina Syndrome (CES) is a rare but serious spinal condition requiring urgent diagnosis and management. Physiotherapists in UK musculoskeletal (MSK) services increasingly encounter suspected CES cases, but little is known about their clinical decision-making and referral practices. This study aimed to examine the clinical decision-making processes of UK physiotherapists when presented with three clinical vignettes of suspected CES and to identify themes in referral...

Mar 17, 2026Read Abstract →

Adverse events among older adults receiving chiropractic spinal manipulation and related treatments: an updated systematic review

No abstract

Mar 17, 2026Read Abstract →

Dose reduction does not impact precision of CT-RSA in tibial components in total knee arthroplasty: a randomized controlled trial

CONCLUSION: The findings confirm that reducing the effective radiation dose from 0.05 mSv to 0.01 mSv does not compromise the precision of CT-RSA for tibial components in TKA. The results further support the use of low-dose CT-RSA protocols in clinical studies, enabling substantial reduction in patient radiation exposure without loss of precision.

Mar 17, 2026Read Abstract →

Molecular markers of antimalarial drug resistance in pfk13, pfmdr1, pfdhfr, and pfdhps genes of Plasmodium falciparum in a rural municipality in Cubal, Benguela Province, Angola (2022-2023)

CONCLUSIONS: This study provides an updated molecular profile of antimalarial resistance in a rural area of Angola. No validated or candidate pfk13 markers of artemisinin resistance were identified. However, the predominance of pfmdr1 haplotypes linked to reduced lumefantrine susceptibility raises concerns regarding AL efficacy. Although SP remains suitable for IPTp, the presence of the "fully resistant" haplotype (IRNGE) of pfdhfr/pfdhps highlight potential risks to long-term effectiveness....

Mar 17, 2026Read Abstract →

Histopathological, molecular, and phylogenetic analyses of Echinococcus species isolated from humans in Mongolia, 2010-2024

Echinococcosis in humans caused by hydatid cyst of Echinococcus spp., remains a significant public health concern in Mongolia. In this study, we aimed to characterize the epidemiology, histopathological features, and molecular diversity of Echinococcus isolates from human infections. A retrospective analysis of surgically confirmed cases diagnosed between 2010 and 2024 was conducted. A histopathological examination of resected or biopsied cyst material was employed to assess cyst morphology and...

Mar 16, 2026Read Abstract →

Questions and issues of non-ventilated hospital acquired pneumonia: an opinion document

BACKGROUND: Non-ventilated hospital-acquired pneumonia (NV-HAP) is a significant cause of morbidity and mortality within healthcare settings. Despite advancements in diagnostic and therapeutic approaches over recent decades, the supporting evidence for diagnostic criteria remains limited. Information regarding the etiology of this condition is scarce, and many methodological aspects related to the collection and analysis of respiratory samples are still under debate. Furthermore, recommendations...

Mar 16, 2026Read Abstract →

An Update on the Therapeutic Potential of Bixin and Norbixin Apocarotenoids

Plants have been a central source of natural resources for humanity with all kinds of uses and applications: food, cosmetics, natural remedies and medicines, dyes, textiles, construction materials, ornamental uses, and the extraction of various compounds, including natural pigments. Within pigments, there are four major groups of interest: anthocyanins, chlorophylls, betalains, and carotenoids. Carotenoids are characterized by being formed by relatively long hydrocarbon chains (25 - 50 C), which...

Mar 16, 2026Read Abstract →

Infection Control in Optometric Practice: Evaluating the Impact of Guidelines on Knowledge, Attitude and Practice Behaviours

CONCLUSIONS: Engagement with IC guidelines significantly improved knowledge among Australian optometrists but did not translate into behaviour change. Findings highlight the need for multifaceted, theory-informed implementation strategies that address environmental and motivational barriers, alongside provision of trusted resources, to embed evidence-based IC practices in optometry.

Mar 16, 2026Read Abstract →

An Updated Review of Utilization Patterns of Sacroiliac Joint Interventions in the Fee-for-service (ffs) Medicare Population from 2000 to 2022

No abstract

Mar 16, 2026Read Abstract →

Effects of propolis supplementation on blood glucose and lipid profiles in individuals with metabolic syndrome and type 2 diabetes: a systematic review and meta-analysis

CONCLUSION: These findings suggest that propolis supplementation may modestly improve glycemic control and reduce TG levels in individuals with T2DM and MetS. However, the limited number of available studies and relatively small sample sizes highlight the need for large, high-quality RCTs to verify these findings and clarify the metabolic effects of propolis.

Mar 16, 2026Read Abstract →

An updated checklist of mosquitoes (Diptera, Culicidae) of Ecuador: new records and public health significance

Mosquitoes are major vectors of human and animal diseases, making their accurate identification essential for vector surveillance and control. However, morphological identification has often been challenging, requiring taxonomic expertise and well-preserved specimens. Molecular markers, particularly DNA barcoding, offer an effective alternative for identifying both adult and immature stages. Ecuador is one of the most biodiverse countries in the world, a diversity that is also evident in its...

Mar 16, 2026Read Abstract →

An initial G value of hydrated electrons updated by a dynamic Monte Carlo simulation

In the radiolysis of water vapour, we can easily categorise ionisation and electronic excitation; however, the ratio of ionisation and electronic excitation for liquid water remains uncertain. The ratio is intrinsically related to the kind of radiolytic species generated. The complexity of subsequently induced DNA damage in a living cell exposed to radiation depends on the type of radiolytic species generated. To address this critical issue, we estimate the ratio of ionisation and electronic...

Mar 16, 2026Read Abstract →

Genetics in Hypertrophic Cardiomyopathy: An Evolving Clinical Landscape

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and is characterised by unexplained increased wall thickness. Traditionally considered a monogenic disorder, emerging evidence highlights its complex genetic architecture. Genetic testing is now a cornerstone for diagnosis and family screening, although its prognostic and therapeutic impact at the individual level remains limited at present but is expected to grow as more comprehensive approaches are developed. Aimed...

Mar 16, 2026Read Abstract →

Tooth loss and infrequent brushing significantly elevate gastric cancer risk: an updated systematic review and meta-analysis with heterogeneity exploration

CONCLUSION: This study solidifies poor oral hygiene as a significant risk factor for GC. The marked geographic disparity offers novel insights for developing targeted primary prevention strategies, underscoring the importance of integrating oral health into general cancer prevention initiatives.

Mar 16, 2026Read Abstract →

Candidate treatments for long COVID: a narrative review of expert and patient-driven priorities

CONCLUSION: This review prioritises and maps candidate treatments for long COVID. There was insufficient direct evidence to inform clinical recommendations. Rather, the treatments presented in this review represent those that could be rigorously tested in clinical trials as they show biological plausibility and/or are feasible and acceptable to people with lived experience and clinicians.

Mar 16, 2026Read Abstract →