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30 results found for "Research"
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30
Calcium: Sources, benefits, and role in bone health
Calcium is an essential mineral that is vital for various bodily functions, including bone health, muscle contraction, nerve function, and blood clotting. In this article, we will discuss the sources, benefits, and role of calcium in bone health, as well as recent research […]
By Liza Nagarkoti
Experiences of individuals with chronic illnesses or complex health needs in navigating the healthcare system, including challenges with care coordination and access to specialists
This research report examines the experiences of individuals with chronic illnesses or complex health needs in navigating the healthcare system, focusing on the challenges they face in terms of care coordination and access to specialists. The report includes examples from Nepal to provide context a
By Dr. Ram Prasad Neupane
One in Three Pregnant Women in Pokhara Experiencing SevereStress, New Study Shows
Pokhara, Nepal — February 9, 2026A new study from Gandaki Medical College has revealed that a significant number of pregnant women in Pokhara are struggling with high levels of stress and anxiety—an issue researchers say has been largely overlooked in Nepal’s maternal health system. Published in the Nepal […]
By Astha Paudel
Gynecological health and reproductive issues
Gynecological health and reproductive issues are essential aspects of women’s health. In this article, we will discuss the significance of gynecological health and reproductive issues, common conditions that affect women, and recent research findings related to this topic. Importance of Gynecologic
By Dr. Deepak Shrestha
How Organs-on-a-Chip and Bioprinting are Redefining Human Medicine
Organs-on-a-Chip: The Future of Drug Discovery and Personalized Medicine Animal models fail nearly 90% of the time in predicting human drug responses. A new wave of microfluidics, bioprinting, and stem‑cell engineering is transforming biomedical research. From lung‑on‑a‑chip to vascularized kidney organoids and patient‑specific iPSC models, micro‑physiological systems are reshaping toxicology, pharmacology, and regenerative medicine. This article explores the breakthroughs driving this shift — and what it means for the future of human‑relevant science.
By Astha Paudel
Macronutrients Metabolic Regulation and Biosynthesis
Macronutrients, including carbohydrates, proteins, and fats, are essential for energy production, growth, and maintenance of bodily functions. The metabolism and biosynthesis of macronutrients play a crucial role in regulating energy balance and maintaining homeostasis. This article explores recent research findings on the metabolic regulation and biosynthesis of macronutrients. Carbohydrate Metabolism: Carbohydrate metabolism involves the breakdown […]
By Alisha Shrestha
Allergies in children and how to manage them
Research findings on allergies in children have contributed to a better understanding of their causes, symptoms, and effective management strategies. This article explores some of these research-backed findings and recommendations for managing allergies in children, supported by references. Understanding Allergies in Children: Allergies occur when the immune system reacts abnormally to harmless substances, such as […]
By Liza Nagarkoti
Medical interventions for obesity management
When traditional diet and exercise reach a plateau, medical interventions offer a science backed secondary layer of defense against obesity. From the appetite regulating power of pharmacotherapy to the metabolic transformations of bariatric surgery and minimally invasive endoscopic procedures, modern medicine provides powerful tools to tackle the biological hurdles of weight loss. Supported by landmark research from JAMA and the NEJM, these clinical pathways when combined with comprehensive lifestyle coaching enable sustainable, long term health improvements and a reduced risk of chronic disease.
By Liza Nagarkoti
Cultural competency in healthcare
Cultural competency in healthcare is an essential aspect of providing quality and equitable care to diverse patient populations. It involves understanding and respecting the beliefs, values, customs, and practices of individuals from different cultures. This essay explores the significance of cultural competency in healthcare and highlights research findings that support its importance in improving patient […]
By Samina Dhital
The benefits of regular exercise
Regular exercise has numerous benefits for our physical and mental health. From improving heart health to reducing stress and anxiety, exercise can positively impact many aspects of our lives. In this article, we will explore some of the benefits of regular exercise and discuss the latest research on the topic. Improved heart health: Regular exercise […]
By Liza Nagarkoti
Mindfulness and meditation techniques for mental well-being
Mindfulness and meditation techniques have gained popularity in recent years as a way to improve mental well-being. They are simple practices that can be done anywhere, anytime, and do not require any special equipment or training. Research has shown that practicing mindfulness and meditation can h
By Sabina Maharjan
Vitamin K: Sources, benefits, and role in blood clotting
Vitamin K is a fat-soluble vitamin that plays a crucial role in blood clotting. In this article, we will discuss the sources, benefits, and role of vitamin K in blood clotting, as well as recent research on its impact on other aspects of […]
By Liza Nagarkoti
Childhood obesity and ways to prevent it
Childhood obesity is a significant public health concern that can have long-term consequences for a child’s physical and mental well-being. This article explores research-backed strategies and tips to prevent childhood obesity, focusing on promoting healthy lifestyles and creating supportive environments for children. Encourage Healthy Eating Habits: Promoting healthy eating habits is crucial in preventing childhood […]
By Liza Nagarkoti
Caregiving for loved ones with chronic conditions
Caring for loved ones with chronic conditions can be challenging and stressful. It is important for caregivers to understand how to provide proper care while also taking care of their own well-being. This research-based article provides an overview of the latest findings on caregiving for loved ones with chronic conditions, including preventative measures that can […]
By Sabina Maharjan
New research in pancreatic cancer screening
Pancreatic cancer is a tough and dangerous type of cancer that’s hard to treat and often doesn’t have a good outcome. But there’s good news: a group of experts from around the world is working hard to create a new program that will help doctors find this cancer early, which could save many lives. T
By Dr. Asmita Rayamajhi
The effects of intermittent fasting on brain function and cognitive performance
New research suggests that intermittent fasting may have positive effects on brain function and cognitive performance. Intermittent fasting is a dietary pattern that involves cycling between periods of fasting and eating. According to a study published in the journal Aging, intermittent fasting was
By Dr. Prakash Paudel
The Growing Crisis of Adolescent Obesity in Nepal : Causes, Consequences, and Solutions
Introduction Nepal is facing a silent but dangerous shift in its public health landscape. While undernutrition remains a critical issue, a new epidemic is emerging: adolescent obesity. My recent research conducted among 72 students at a Kathmandu school revealed that 11.1% were obese and 9.7%
By Liza Nagarkoti
Health technology and innovation
Health technology and innovation are rapidly advancing, revolutionizing healthcare delivery in Nepal. The latest developments in healthcare technology have the potential to enhance patient care, improve health outcomes, and streamline healthcare processes. This summary highlights key advancements and research findings in health technology and innovation in Nepal. Telemedicine and Digital Health: Telemedicine has emerged as […]
By Astha Paudel
Vitamin E: Sources, benefits, and antioxidant properties
Vitamin E is a fat-soluble vitamin that plays an important role in maintaining good health. In this article, we will discuss the sources, benefits, and antioxidant properties of vitamin E, as well as recent research and findings related to this vitamin. Sources of […]
By Liza Nagarkoti
Breaking the Black Box: How Artificial Embryos and Lab-Grown Wombs Are Unlocking the Secrets of Human Life
1. CREST: The Lab-Grown Uterine Scaffold Cell-engineered Receptive Endometrial Scaffold Technology (CREST) is a sophisticated 3D model that recreates the complex layers of the human uterus, including the surface lining and the deeper structural tissue. This platform allows scientists to watch real human embryos and lab-made "blastoids" attach and burrow into the tissue just as they would in the body. By using this model, researchers discovered that a specific molecular "handshake" called PROS1-AXL is essential for the embryo to grow successfully into the uterine wall. 2. Inducible Embryo Models (iSCBEMs) Because natural human embryos are so difficult to access, scientists created iSCBEMs, which are models built entirely from stem cells. These structures are "inducible," meaning researchers can trigger them to form critical parts of an early pregnancy, such as the yolk sac and the amniotic cavity. These models provide a highly reproducible way to study the first few weeks of life without the ethical and logistical hurdles of using donated human embryos. 3. The Hidden "Forces" of Implantation Groundbreaking research has revealed that human embryos aren't just passive—they actively pull themselves into the uterus using physical traction. By sensing the stiffness of the mother's tissue, a process called mechanosensitivity, the embryo uses tiny "grips" to anchor itself and reorganize the surrounding environment. This discovery suggests that many miscarriages might happen not because of a chemical error, but because the embryo simply couldn't exert enough physical force to burrow in. 4. "Apical-Out" Organoids: Reversing the Map For years, lab-grown uterine tissues (organoids) grew "inside-out," making it impossible for embryos to touch the surface they normally stick to. New "apical-out" models flip this structure, exposing the receptive surface to the outside so that embryos can land and attach naturally. These models even grow tiny structures called pinopodes, which act like landing pads for the embryo, making the lab environment look and act like a real womb. 5. The 28-Day Rule and Research Ethics As lab-grown embryo models become more realistic, the ESHRE Ethics Committee has proposed extending the legal research limit from 14 days to 28 days. This extension would allow scientists to study the very beginning of organ development and the early heart, which are currently "black boxes" of human science. While these models are not yet considered equivalent to "real" embryos, they offer a way to solve the mysteries of birth defects and infertility while following strict moral guidelines. 6. Solving Infertility with Personalized Models Implantation failure is a major cause of infertility, responsible for nearly 60% of early pregnancy losses. Scientists are now using these artificial models to create "patient-specific" uterine linings to test why a specific person's body might be rejecting a pregnancy. This technology could lead to new, non-hormonal contraceptives or personalized treatments that significantly improve the success rates of IVF.
By Dr. Asmita Pandey
New Study Reveals Hidden Environmental Drivers Behind Nepal’s Ongoing Cholera Battle
Nepal has nearly eliminated open defecation, but a new 10‑year study warns that worsening water scarcity and declining handwashing access are now driving cholera risk. After a major 2021 outbreak, researchers say climate‑driven droughts and floods, limited safe drinking water, and gaps in basic hygiene are undermining progress. They argue that Nepal’s cholera strategy must shift from toilet construction to ensuring reliable clean water and handwashing for every household.
By Sanjogta Thapa Magar
Mental health and well-being during pregnancy and postpartum
Mental health during the perinatal period is vital for both mother and child, as poor well-being can lead to risks like preterm birth and developmental delays. This article identifies common challenges such as hormonal shifts, sleep deprivation, and social isolation. It also cites recent research showing that routine screening, regular exercise, and strong social support systems are effective interventions for improving maternal health outcomes and protecting the baby’s development.
By Sabina Maharjan
A Critical Review of How Common Vaginal Infections Invite Lifelong HSV-2
The 2026 systematic review and meta-analysis by Taylor N. Whitt et al., published in Viruses, identifies Bacterial Vaginosis (BV) as a primary "biological gateway" that increases a woman's risk of acquiring HSV-2 by up to 91%. By synthesizing data from prospective longitudinal studies, the researchers demonstrated that the transition from a protective Lactobacillus-dominant environment to a dysbiotic state "unzips" natural defenses through the enzymatic degradation of mucosal barriers and the recruitment of inflammatory target cells. Especially critical in regions with high BV prevalence like South Asia, these findings emphasize the urgent need to shift from treating acute symptoms to a preventative model focused on long-term microbiome restoration to block viral entry.
By Dr. Asmita Pandey
Diet-Nutrient and Drug Interactions
Dietary supplements are widely consumed by individuals seeking to improve their health or manage specific conditions. However, it is important to consider potential interactions between dietary supplements, nutrients, and medications. This article explores recent research findings on diet-nutrient and drug interactions, with a focus on dietary supplements, providing insights into their potential effects and implications […]
By Anusha Bastola
The Chemistry of Feeling: Why Your Mood Starts in the Gut
We’ve all heard the phrase “you are what you eat,” but we rarely take it literally. Usually, we think of it in terms of waistlines or heart health. However, a growing body of research suggests that our diet is actually the primary architect of our emotional world—proving that your mood starts in th
By Sanjogta Thapa Magar
The Impact of the Ketogenic Diet on Epigenetics in Controlling Seizures
Reviewed byDr. Prakash Paudel, FCPS,Consultant Neurosurgeon & Spine SpecialistIntroduction: The ketogenic diet, a high-fat, low-carbohydrate, and moderate-protein eating plan, has gained recognition as an effective therapy for reducing seizures in individuals with epilepsy. While the exact mechanisms underlying its anticonvulsant effects are still being elucidated, emerging research suggests that the ketogenic diet may exert its […]
By Dr. Prakash Paudel
The impact of caffeine and alcohol on sleep
Many of us rely on caffeine to get us through the day, and a nightcap to help us wind down before bed. However, recent research has shown that consuming caffeine and alcohol can have a significant impact on our sleep, affecting both the quality and quantity of our rest. Caffeine, a stimulant found in coffee, […]
By Liza Nagarkoti
Telemedicine and virtual healthcare
Telemedicine and virtual healthcare have emerged as transformative solutions in healthcare delivery, especially in recent years. With advancements in technology and the increased availability of digital platforms, telemedicine offers an innovative approach to providing remote medical services, consultation, and monitoring. This article aims to explore the effectiveness and challenges of telemedicine based on recent research […]
By Astha Paudel
What are the benefits of Knotweed tea ?
Knotweed, also known as Japanese knotweed (Fallopia japonica), is a plant that has been used in traditional medicine for centuries. It offers several potential benefits due to its unique chemical composition. However, it is important to note that further research is needed to fully understand and validate these benefits. Here are some potential benefits of […]
By Liza Nagarkoti
How Nepal’s medical research is quietly transforming treatment options
For a long time, Nepal’s healthcare story has been framed around limitations—limited resources, limited access, and limited infrastructure. But there’s another story unfolding, one that doesn’t always make headlines: a quiet, determined rise in medical research led by Nepali clinicians and scientis
By Dr. Ram Prasad Neupane